Red Bull's Sebastian Vettel got his title defence off to a perfect start with a pole-to-flag victory in the Australian Grand Prix.
Lewis Hamilton finished second to seal McLaren's turnaround in form but team-mate Jenson Button was sixth after being penalised for cutting a corner.
A brilliant start from Russian Vitaly Petrov propelled him to his first podium with third for Renault.
Scot Paul di Resta finished with 12th for Force India on his debut.
Ferrari's Fernando Alonso jumped Mark Webber's Red Bull in his final pit stop to take fourth place from the Australian, who could only equal his career-best finish at his home race.
There was more frustration for Mercedes as both Michael Schumacher and Nico Rosberg retired from the race.
It was a faultless race from the man intent on chasing Schumacher's record seven championship as Vettel pulled clear at the start, stopped twice and ran much of the race on his own.
"A stunning performance from the man who's led every lap of the last three grands prix," said BBC F1 commentator Martin Brundle.
"That is a calm and steely Vettel, and frankly I don't think anyone was going to beat him."
Ominously for the rest of the field, team principal Christian Horner revealed after the race that neither of the Red Bull cars was running a Kers boost system.
"It was a fantastic day for Sebastian and the team, he was dominant in qualifying and totally dominant today," said Horner.
"We felt Kers was a potential risk, and we made a decision not to run it. It didn't look like we needed it."
Vettel himself insisted the race had not been as straightforward as it appeared.
"It was not easy, the start was crucial," he said.
"I had a good getaway, but didn't know if it was enough until I saw Lewis and Mark [Webber] battling for position.
"After my stop it was crucial to get past jenson, which I could do immediately, so that was very, very important. There were a lot of things to learn today and we need to have another look at the race."
Vettel had already built a 2.6-second lead at the end of the first lap while others toiled behind him.
Button found himself down in sixth after losing position to Ferrari's Felipe Massa and Petrov, who had brilliantly nosed his Renault up from sixth on the grid.
As the race developed, Button tried time and again to pass Massa, and even activated the moveable rear wing which is designed to aid overtaking, but the Brazilian defended deftly and Button was left asking his team over the radio; 'How's he getting away from me?"
There were more headaches to come for Button when he cut a chicane in an attempt to pass Massa and was subsequently handed a drive-through penalty.
"There's no question that he gained an advantage," said BBC analyst David Coulthard.
"He knew that two doesn't go into one around that curve. He had to go off track and had to pay a penalty for that."
Button had a stab at holding up Vettel - who had pitted for the first of his two stops to leave Hamilton at the front for McLaren - before serving his penalty but the German soon flew past him and comfortably resumed his lead when Hamilton came in.
After his stop-go penalty Button fed back in 12th but he crossed the line in sixth after what Brundle described as an "adventurous race".
Despite Button's busy day, he and team-mate Hamilton will be relieved that McLaren's hard work at their Woking factory to turn a winter marred by a lack of pace and unreliability into a competitive start to the campaign.
Hamilton managed his race well and took his car across the line for second despite warnings from his team that his car was damaged. It quickly became evident the undertray and floor of the car was broken, which as Hamilton pointed out afterwards, badly affected the amount of downforce.
"To come away from here with a second is a great achievement - in the end I was simply trying to nurse the car home," Hamilton said.
Renault proved they had taken a step forward over the winter, in part thanks to their innovative car design with its front-exiting exhausts, as Petrov collected third place with a cool drive.
The Russian repeated his trick from the season-ending Abu Dhabi Grand Prix by holding off a looming Alonso.
Robert Kubica was second for Renault at last year's race in Melbourne and Petrov suggested he is capable of leading the time on the track in the absence of Kubica, who is recovering from serious injuries in a rallying accident.
Petrov's Renault team-mate Nick Heidfeld, the stand-in for Kubica, finished a lowly 14th,
Alonso had got himself caught up in Button's wake as the McLaren went backwards off the line and the Ferrari ran wide into the first corner.
The Spaniard slid to 10th but he picked his way smoothly through the field before passing Webber for fourth place.
Both drivers were on a three-stop strategy but Webber conceded fourth place to Alonso on the final stop after he ran wide on his return to the parkland circuit.
There had been a lot of talk about tyre strategy and management in the build-up to the race as this season's Pirellis tyres had been designed too degrade more quickly than 2010's Bridgestones.
Most of the field made straightforward two-stop strategies work but Sauber raised eyebrows as Mexican rookie Sergio Perez stopped just once on his way to seventh.
Mercedes arrived in Melbourne with high hopes of a podium but their weekend ended miserably inside two laps.
Schumacher, who had a puncture at the start, was retired from the race as a precaution before his old Ferrari team-mate Rubens Barrichello added to his misery by ploughing his left wheel into the side of Nico Rosberg's Mercedes, sending him back to the garage for good.
"I had a good start but someone knocked on my rear right and there were consequences from that," Schumacher told BBC Sport.
"I had an entertaining few laps but the team quite rightly for safety decided that I should come in."
Barrichello was the second driver to serve a drive-through penalty for his move on Rosberg and later had to retire from the race.